This article has an interesting new twist
on the cholesterol debate: High
cholesterol in midlife raises risk of
late-life dementia ... Here is the first paragraph:
Elevated cholesterol levels in midlife – even levels
considered only borderline elevated – significantly increase the risk of
Alzheimer's disease and vascular dementia later in life, according to a new
study by researchers at Kaiser Permanente's Division of Research and the
University of Kuopio in Finland. The study appears in the journal Dementia
& Geriatric Cognitive Disorders. The four-decade study of 9,844 men and
women found that having high cholesterol
in midlife (240 or higher milligrams per deciliter of blood) increases, by
66 percent, the risk for Alzheimer's disease later in life. Even borderline cholesterol levels (200 –
239 mg/dL) in midlife raised risk for late-life vascular dementia by nearly
the same amount: 52 percent. Vascular dementia, the second most common form of
dementia after Alzheimer's disease, is a group of dementia syndromes caused by
conditions affecting the blood supply to the brain. Scientists are still trying
to pinpoint the genetic factors and lifestyle causes for Alzheimer's disease.
Here is the
interesting twist from my perspective. We are bombarded with “facts” and media
saying that any cholesterol reading over 200 should be treated with a
cholesterol lowering drug that will destroy your muscles, including your heart.
Yet in this study, high cholesterol is 240 or higher, not 200. Borderline cholesterol
is 200 to 239. So what does that mean for the “oh my gosh, your cholestrol is
over 200 and you need drugs” diagnosis?
What it means
to me is that correlation does not equal causation. Here are a couple of other
Kaiser demential-related studies from the article:
This study is part of an ongoing body of research at
Kaiser Permanente to better understand the risk and protective factors for
dementia. Dr. Whitmer recently authored two dementia-related studies: one that
found a larger abdomen in midlife increases risk of late-life dementia, and one
that showed that low blood sugar events in elderly patients with type 2
diabetes increase their risk for dementia. Another Kaiser Permanente study, led
by Valerie Crooks of Kaiser Permanente in Southern California, found that
having a strong social network of friends and family appears to decrease risk
for dementia.
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